La electroforesis capilar como una nueva estrategia en la medicina y el diagnóstico clínico / Capillary electrophoresis, a new diagnostic tool
Rev. méd. Chile
; 137(7): 946-956, jul. 2009. ilus, tab
Article
em Es
| LILACS
| ID: lil-527136
Biblioteca responsável:
BR1.1
ABSTRACT
Capillary electrophoresis (CE) may replace many conventional clinical laboratory methods, such as electrophoresis, Southern blotting, sequencing and HPLC (High-performance liquid chromatography). It is an ideal technique due to analytical speed, the possibility of handling great amount of samples, its capacity to separate small molecules according to their size, charge, hydrophobic and stereo-specificity its good reproducibility the use of small amounts of sample and reagents, its low costs and easy handling. The diagnosis of hereditary diseases or the predisposition to polygenic diseases related to specific mutations or polymorphisms can be carried out with this method. In clinical laboratories, this technique is being used for the analysis of several substrates present in urine or serum and for the diagnosis of some infectious agents. It is also a firsthand tool in forensic medicine for human identification and anthropology.
Palavras-chave
Texto completo:
1
Base de dados:
LILACS
Assunto principal:
Eletroforese Capilar
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
Es
Revista:
Rev. méd. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
México