Differential mortality risk of postprocedural creatine kinase-MB elevation following successful versus unsuccessful stent procedures.
J Am Coll Cardiol
; 44(6): 1210-4, 2004 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-15364321
ABSTRACT
OBJECTIVES:
This study was designed to evaluate the effect of periprocedural myocardial infarction (MI) on mortality according to success of the stent procedure.BACKGROUND:
The mortality effect of periprocedural MI relative to successful versus unsuccessful procedures has not been examined.METHODS:
All-cause mortality during the first year was evaluated prospectively among 5,850 patients from coronary stent clinical trials. Myocardial infarction was classified according to creatine kinase-MB level as type 1 (>1 but <3 times normal), type 2 (>or=3 butRESULTS:
Myocardial infarction was more frequent after unsuccessful procedures (69.6% vs. 20.4%, p < 0.001). Mortality during the first year was higher in patients with MI (2.8% vs. 1.7%, p = 0.01), but the effect was significant only for type 3 MI (4.7% vs. 1.7%, p = 0.008). Moreover, the mortality difference for any MI was confined to patients with unsuccessful procedures (13.1% vs. 0%, p = 0.03), with no significant effect among patients with otherwise successful procedures (2.1% vs. 1.7%, p > 0.20). The independent predictors of mortality were unsuccessful procedure (p < 0.001), diabetes mellitus (p = 0.001), history of prior MI (p = 0.003), multivessel disease (p = 0.006), and advancing age (p < 0.001), but not periprocedural MI.CONCLUSIONS:
The association of periprocedural MI with increased mortality during the first year following stent placement was confined to patients with unsuccessful procedures.
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Base de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
/
Stents
/
Creatina Quinase
/
Isoenzimas
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Am Coll Cardiol
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Estados Unidos