Invasive pulmonary aspergillosis in patients with decompensated cirrhosis: case series.
BMC Gastroenterol
; 7: 2, 2007 Jan 31.
Article
em En
| MEDLINE
| ID: mdl-17266747
ABSTRACT
BACKGROUND:
Opportunistic invasive fungal infections are increasingly frequent in intensive care patients. Their clinical spectrum goes beyond the patients with malignancies, and for example invasive pulmonary aspergillosis has recently been described in critically ill patients without such condition. Liver failure has been suspected to be a risk factor for aspergillosis. CASE PRESENTATION We describe three cases of adult respiratory distress syndrome with sepsis, shock and multiple organ failure in patients with severe liver failure among whom two had positive Aspergillus antigenemia and one had a positive Aspergillus serology. In all cases bronchoalveolar lavage fluid was positive for Aspergillus fumigatus. Outcome was fatal in all cases despite treatment with voriconazole and aggressive symptomatic treatment.CONCLUSION:
Invasive aspergillosis should be among rapidly raised hypothesis in cirrhotic patients developing acute respiratory symptoms and alveolar opacities.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Aspergilose
/
Aspergillus fumigatus
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Fungemia
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Falência Hepática
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Cirrose Hepática Alcoólica
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
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Male
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Middle aged
Idioma:
En
Revista:
BMC Gastroenterol
Assunto da revista:
GASTROENTEROLOGIA
Ano de publicação:
2007
Tipo de documento:
Article