NIAID resources for developing new therapies for severe viral infections.
Antiviral Res
; 78(1): 51-9, 2008 Apr.
Article
em En
| MEDLINE
| ID: mdl-18061283
ABSTRACT
Severe viral infections, including hemorrhagic fever and encephalitis, occur throughout the world, but are most prevalent in developing areas that are most vulnerable to infectious diseases. Some of these can also infect related species as illustrated by the threatened extinction of gorillas by Ebola infection in west and central Africa. There are no safe and effective treatments available for these serious infections. In addition to the logistical difficulties inherent in developing a drug for infections that are sporadic and occur mainly in the third world, there is the overwhelming barrier of no hope for return on investment to encourage the pharmaceutical industry to address these unmet medical needs. Therefore, the National Institute of Allergy and infectious Disease (NIAID) has developed and supported a variety of programs and resources to provide assistance and lower the barrier for those who undertake these difficult challenges. The primary programs relevant to the development of therapies for severe viral infections are described and three case studies illustrate how they have been used. In addition, contact information for accessing these resources is supplied.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Apoio à Pesquisa como Assunto
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Viroses
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Desenvolvimento de Programas
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National Institute of Allergy and Infectious Diseases (U.S.)
Limite:
Animals
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Humans
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Antiviral Res
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Estados Unidos