A randomized intervention trial to reduce the lending of used injection equipment among injection drug users infected with hepatitis C.
Am J Public Health
; 98(5): 853-61, 2008 May.
Article
em En
| MEDLINE
| ID: mdl-18382005
ABSTRACT
OBJECTIVES:
We evaluated the efficacy of a peer-mentoring behavioral intervention designed to reduce risky distributive injection practices (e.g., syringe lending, unsafe drug preparation) among injection drug users with hepatitis C virus (HCV) infection.METHODS:
A randomized trial with a time-equivalent attention-control group was conducted among 418 HCV-positive injection drug users aged 18 to 35 years in 3 US cities. Participants reported their injection-related behaviors at baseline and at 3- and 6-month follow-ups.RESULTS:
Compared with the control group, intervention-group participants were less likely to report distributive risk behaviors at 3 months (odds ratio [OR]=0.46; 95% confidence interval [CI]=0.27, 0.79) and 6 months (OR=0.51; 95% CI=0.31, 0.83), a 26% relative risk reduction, but were no more likely to cite their HCV-positive status as a reason for refraining from syringe lending. Effects were strongest among intervention-group participants who had known their HCV-positive status for at least 6 months. Peer mentoring and self-efficacy were significantly increased among intervention-group participants, and intervention effects were mediated through improved self-efficacy.CONCLUSIONS:
This behavioral intervention reduced unsafe injection practices that may propagate HCV among injection drug users.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Assunção de Riscos
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Terapia Comportamental
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Abuso de Substâncias por Via Intravenosa
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Uso Comum de Agulhas e Seringas
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Hepatite C
Tipo de estudo:
Clinical_trials
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Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Male
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Am J Public Health
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Estados Unidos