Potential effect of an apoprotein B-based algorithm on management of new patients with hypertriglyceridemia referred to a specialty lipid clinic.
Clin Cardiol
; 32(5): 251-5, 2009 May.
Article
em En
| MEDLINE
| ID: mdl-19452482
ABSTRACT
BACKGROUND:
In patients with hypertriglyceridemia, non-high density lipoprotein cholesterol (nonHDL-C) is a targeted goal. However, apoprotein B100 (apoB) may be superior in predicting cardiovascular risk so we assessed the utility of an apoB-based.METHODS:
New patients (n = 125) who had both apoB and standard lipids measured on the same day were included and we determined the concordances of having achieved goal lipid levels based upon proposed apoB versus nonHDL-C (ATP III) targets in patients with elevated TG (>or=150 mg*dl(-1)) levels.RESULTS:
Although apoB was correlated with nonHDL-C (r = 0.47, pCONCLUSIONS:
Our findings confirm that the majority of patients referred with hypertriglyceridemia would be managed differently by following an apoB-based treatment algorithm compared to ATP III guidelines. Although many patients would be candidates for more intense therapy, many would be treated less aggressively.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hipertrigliceridemia
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Apolipoproteína B-100
Tipo de estudo:
Etiology_studies
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Guideline
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Clin Cardiol
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Estados Unidos