Lambert-Eaton myasthenic syndrome revealing an abdominal neuroblastoma.
J Pediatr Surg
; 44(8): E5-7, 2009 Aug.
Article
em En
| MEDLINE
| ID: mdl-19635290
ABSTRACT
Lambert-Eaton myasthenic syndrome is a paraneoplastic syndrome that may reveal a primitive tumor. Neuroblastoma in children and small cell lung carcinoma in adults are the leading tumors revealed or expressed by paraneoplastic phenomena. The clinical neurologic manifestations of Lambert-Eaton myasthenic syndrome are muscular weakness, sleepiness, absence of reflexes, and dysautonomia. Neurologic manifestations are explained by the induction of an autoimmune response because of the presence of antigens that are expressed by the tumor. Neurologic paraneoplastic disorders may also be the result of toxicity of drugs, coagulopathy, infection, or metabolic diseases. We describe the case of a 13-month-old child with unusual neurologic symptoms because of the presence of an abdominal neuroblastoma.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Síndrome Miastênica de Lambert-Eaton
/
Neoplasias Abdominais
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Neuroblastoma
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
/
Infant
Idioma:
En
Revista:
J Pediatr Surg
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Canadá