Comparison of magnetic resonance imaging findings in anterior cruciate ligament grafts with and without autologous platelet-derived growth factors.
Arthroscopy
; 26(1): 50-7, 2010 Jan.
Article
em En
| MEDLINE
| ID: mdl-20117627
ABSTRACT
PURPOSE:
To determine whether the use of platelet-rich plasma gel (PRPG) affects magnetic resonance imaging (MRI) findings in the anterior cruciate ligament (ACL) graft during the first year after reconstruction.METHODS:
A prospective single-blinded study of 50 ACL reconstructions in 50 patients was performed. In group A (study group) PRPG was added to the graft with a standardized technique, and in group B (control group) no PRPG was added. An MRI study was performed postoperatively between 3 and 9 months in group A and between 3 and 12 months in group B. The imaging analysis was performed in a blind protocol by the same radiologist.RESULTS:
The mean heterogeneity score value at the time of MRI, assigned by the radiologist, was 1.14 in group A and 3.25 in group B. Both groups were comparable in terms of sex and age (P < .05). The mean time to obtain a completely homogeneous intra-articular segment in group A (PRPG added) was 177 days after surgery, and it was 369 days in group B. Using the quadratic predictive model, these findings show that group A (PRPG added) needed only 48% of the time group B required to achieve the same MRI image (P < .001).CONCLUSIONS:
ACL reconstruction with the use of PRPG achieves complete homogeneous grafts assessed by MRI, in 179 days compared with 369 days for ACL reconstruction without PRPG. This represents a time shortening of 48% with respect to ACL reconstruction without PRPG.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Artroscopia
/
Traumatismos em Atletas
/
Tendões
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Cicatrização
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Fator de Crescimento Derivado de Plaquetas
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Imageamento por Ressonância Magnética
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Ligamento Cruzado Anterior
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Transplante Ósseo
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Ligamento Patelar
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Procedimentos de Cirurgia Plástica
Tipo de estudo:
Clinical_trials
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Diagnostic_studies
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Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
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Female
/
Humans
/
Male
Idioma:
En
Revista:
Arthroscopy
Assunto da revista:
ORTOPEDIA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Chile