Identification of target cells for Goose parvovirus infection in the immune system organs.
Acta Virol
; 54(3): 211-5, 2010.
Article
em En
| MEDLINE
| ID: mdl-20822314
Target cells for Goose parvovirus (GPV) in natural infection are still unknown. In this study, immune system organs namely the spleen, bone marrow, thymus, bursa of Fabricius, and blood of experimentally GPV-infected goslings were examined by an immunoassay and flow cytometry for the presence of viral antigen and by a PCR for viral genome. The results indicated that the virus replicated in some cells of the spleen and bone marrow, but not in peripheral blood lymphocytes (PBLs). These data suggested that some cell populations in the spleen and bone marrow were targets for GPV infection. In addition, the immunoassay used for the detection of GPV was found comparable with a PCR in reliability and sensitivity.
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Base de dados:
MEDLINE
Assunto principal:
Doenças das Aves Domésticas
/
Dependovirus
/
Infecções por Parvoviridae
/
Sistema Imunitário
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
Acta Virol
Ano de publicação:
2010
Tipo de documento:
Article