Adaptive evolution of multiple traits through multiple mutations at a single gene.
Science
; 339(6125): 1312-6, 2013 Mar 15.
Article
em En
| MEDLINE
| ID: mdl-23493712
ABSTRACT
The identification of precise mutations is required for a complete understanding of the underlying molecular and evolutionary mechanisms driving adaptive phenotypic change. Using plasticine models in the field, we show that the light coat color of deer mice that recently colonized the light-colored soil of the Nebraska Sand Hills provides a strong selective advantage against visually hunting predators. Color variation in an admixed population suggests that this light Sand Hills phenotype is composed of multiple traits. We identified distinct regions within the Agouti locus associated with each color trait and found that only haplotypes associated with light trait values have evidence of selection. Thus, local adaptation is the result of independent selection on many mutations within a single locus, each with a specific effect on an adaptive phenotype, thereby minimizing pleiotropic consequences.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pigmentação
/
Adaptação Fisiológica
/
Peromyscus
/
Herança Multifatorial
/
Evolução Biológica
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Science
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos