Biomarcadores; Metilação de DNA/genética; DNA Mitocondrial/genética; Epigênese Genética; Humanos; Mitocôndrias/genética; Mitocôndrias/metabolismo; S-Adenosil-Homocisteína

5-MTHF; 5-hydroxymethylcytosine; 5-methyl-tetrahydrofolate; 5-methylcytosine; 5hmC; 5mC; AD; AIMs; ALS; Alzheimer disease; Biomarker; CBS; CHARM; CTH; ChIP; DNA methyltransferase; DNMT; DS; Down's syndrome; Epigenetics; Hcy; MAT; MBE; MCA; MMAss; MS; MT; MTHFR; MeDIP and mDIP; Methylation; Mitochondrial DNA; Ms-AP-PCR; MsCC; NAFLD; NASH; PD; Parkinson disease; ROS; S-adenosylhomocysteine; S-adenosylmethionine; SAH; SAH hydrolase; SAHH; SAM; SHMT; TET; TFA; TFB; THF; WGsBs; amplification of inter-methylated sites; amyotrophic lateral sclerosis; chromatin immunoprecipitation; comprehensive high-throughput arrays for relative methylation; cystathionine ß-synthase; cystathionine γ-lyase; homocysteine; methionine adenosyltransferase; methionine synthase; methylated CpG island amplification; methylated DNA immunoprecipitation; methylation-sensitive arbitrarily primed PCR; methylation-sensitive cut counting; methylenetetrahydrofolate reductase; methyltransferase; microarray-based methylation assessment of single samples; mitochondrial DNA; mitochondrial bifunctional enzyme; mtDNA; nDNA; nonalcoholic fatty liver disease; nonalcoholic steatohepatitis; nuclear DNA; reactive oxygen species; serine hydroxymethyltransferase; ten­eleven translocation; tetrahydrofolate; transcription factor A; transcription factor B; whole-genome shotgun bisulfite sequencing