Lifestyle factors associated with the risk of prostate cancer among Pakistani men.
J Ayub Med Coll Abbottabad
; 24(2): 111-5, 2012.
Article
em En
| MEDLINE
| ID: mdl-24397069
ABSTRACT
BACKGROUND:
Age-adjusted incidence of prostate cancer in Pakistan is 5.3 per 100,000 which is relatively low as compared to other Asian countries, but increasing numbers of cases are being reported. Data on risk factors associated with prostate cancer risk among Pakistani men are sparse. The objective of this study was to identify lifestyle factors associated with the risk of prostate cancer in Pakistani men.METHODS:
An unmatched case-control study was conducted in Lahore from February to October 2011. The study enrolled 195 histologically confirmed cases of adenocarcinoma of prostate from Shaukat Khanum Memorial Hospital and Institute of Nuclear Medicine and Oncology Lahore (INMOL) and Lady Reading Hospital. Peshawar, using purposive sampling technique. A total of 390 hospital controls were selected using convenient sampling technique from different teaching hospitals of Lahore after screening with prostate specific antigen levels. A semi-structured interview form was used to collect data through face-to-face interviews. Odds ratio was used as a measure of strength of association and was calculated using unconditional logistic regression.RESULTS:
Farmers were found to be at higher odds of prostate cancer (OR 19.76; 95% CI 5.51-70.80; p < 0.001). No significant association was found with marital status, ethnic background, religious affiliation and consanguineous marriages. Level of physical activity was inversely associated with prostate cancer risk (OR 0.05; 95% CI 0.01-0.26; p < 0.001). Positive association was found with increased red meat consumption (OR 11.82; 95% CI 2.88-48.54; p = 0.001) and dairy products intake (11.76; 95% CI 4.23-32.67; p < 0.001).CONCLUSION:
Red meat consumption, higher dairy products intake and working as farmers are strongly associated with increased odds of prostate cancer among Pakistani men.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Adenocarcinoma
/
Estilo de Vida
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
Limite:
Aged
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Ayub Med Coll Abbottabad
Assunto da revista:
MEDICINA
Ano de publicação:
2012
Tipo de documento:
Article