Nanomolar pyrophosphate detection in water and in a self-assembled hydrogel of a simple terpyridine-Zn2+ complex.
J Am Chem Soc
; 136(15): 5543-6, 2014 Apr 16.
Article
em En
| MEDLINE
| ID: mdl-24494632
ABSTRACT
A simple terpyridine-Zn(II) complex is shown to act as an efficient and highly selective fluorescent sensor for pyrophosphate in water at physiological pH. The sensor complex showed an unprecedented fluorescence response (â¼500 fold increase) and a record nanomolar sensitivity (detectable fluorescent response at 20 nM and LOD â¼ 0.8 nM). It has successfully been used to stain and record confocal fluorescence microscopy images of HeLa cells. Moreover, the complex was found to self-assemble into a hydrogel which was subsequently used to coat disposable paper strips for easy, low-cost detection of pyrophosphate.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Piridinas
/
Zinco
/
Água
/
Difosfatos
/
Hidrogéis
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
J Am Chem Soc
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Finlândia