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Stimulation of the soluble guanylate cyclase (sGC) inhibits fibrosis by blocking non-canonical TGFß signalling.
Beyer, Christian; Zenzmaier, Christoph; Palumbo-Zerr, Katrin; Mancuso, Rossella; Distler, Alfiya; Dees, Clara; Zerr, Pawel; Huang, Jingang; Maier, Christiane; Pachowsky, Milena L; Friebe, Andreas; Sandner, Peter; Distler, Oliver; Schett, Georg; Berger, Peter; Distler, Jörg H W.
Afiliação
  • Beyer C; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
  • Zenzmaier C; Institute for Biomedical Aging Research, University of Innsbruck, Innsbruck, Austria Department of Internal Medicine, Innsbruck Medical University, Innsbruck, Austria.
  • Palumbo-Zerr K; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
  • Mancuso R; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
  • Distler A; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
  • Dees C; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
  • Zerr P; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
  • Huang J; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
  • Maier C; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
  • Pachowsky ML; Department of Trauma and Orthopaedic Surgery, University Erlangen-Nuremberg, Erlangen, Germany.
  • Friebe A; Institute for Physiology, Julius-Maximilians-University Würzburg, Würzburg, Germany.
  • Sandner P; Bayer Health Care, Global Drug Discovery-Common Mechanism Research, Wuppertal, Germany Hannover Medical School, Institute of Pharmacology, Hannover, Germany.
  • Distler O; Department of Rheumatology, University Hospital Zurich, Zürich, Switzerland.
  • Schett G; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
  • Berger P; Institute for Biomedical Aging Research, University of Innsbruck, Innsbruck, Austria.
  • Distler JH; Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.
Ann Rheum Dis ; 74(7): 1408-16, 2015 Jul.
Article em En | MEDLINE | ID: mdl-24567525
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escleroderma Sistêmico / Pele / Transdução de Sinais / Fator de Crescimento Transformador beta / Receptores Citoplasmáticos e Nucleares / Fibroblastos / Guanilato Ciclase Tipo de estudo: Observational_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Escleroderma Sistêmico / Pele / Transdução de Sinais / Fator de Crescimento Transformador beta / Receptores Citoplasmáticos e Nucleares / Fibroblastos / Guanilato Ciclase Tipo de estudo: Observational_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha