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Statins inhibit ABCB1 and ABCG2 drug transporter activity in chronic myeloid leukemia cells and potentiate antileukemic effects of imatinib.
Glodkowska-Mrowka, Eliza; Mrowka, Piotr; Basak, Grzegorz W; Niesiobedzka-Krezel, Joanna; Seferynska, Ilona; Wlodarski, Pawel Krzysztof; Jakobisiak, Marek; Stoklosa, Tomasz.
Afiliação
  • Glodkowska-Mrowka E; Department of Immunology, Medical University of Warsaw, Warsaw, Poland; Department of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Medical University of Warsaw, Warsaw, Poland.
  • Mrowka P; Department of Biophysics and Human Physiology, Medical University of Warsaw, Warsaw, Poland.
  • Basak GW; Department of Hematology, Oncology and Internal Diseases, Medical University of Warsaw, Warsaw, Poland.
  • Niesiobedzka-Krezel J; Department of Hematology, Oncology and Internal Diseases, Medical University of Warsaw, Warsaw, Poland.
  • Seferynska I; Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Wlodarski PK; Department of Histology and Embryology, Medical University of Warsaw, Warsaw, Poland.
  • Jakobisiak M; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.
  • Stoklosa T; Department of Immunology, Medical University of Warsaw, Warsaw, Poland. Electronic address: tomasz.stoklosa@wum.edu.pl.
Exp Hematol ; 42(6): 439-47, 2014 Jun.
Article em En | MEDLINE | ID: mdl-24667683
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Pirimidinas / Benzamidas / Leucemia Mieloide de Fase Crônica / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Transportadores de Cassetes de Ligação de ATP / Proteínas de Neoplasias / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Exp Hematol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Polônia
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Pirimidinas / Benzamidas / Leucemia Mieloide de Fase Crônica / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Transportadores de Cassetes de Ligação de ATP / Proteínas de Neoplasias / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Exp Hematol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Polônia