Assessment of antioxidant and antiproliferative properties of spinach plants grown under low oxygen availability.
J Sci Food Agric
; 95(3): 490-6, 2015 Feb.
Article
em En
| MEDLINE
| ID: mdl-24862450
ABSTRACT
BACKGROUND:
In the human diet, the consumption of fresh fruits and vegetables is important in maintaining good health and in preventing chronic diseases. It is known that plant-derived food is a powerful source of chemopreventive molecules, i.e. antioxidants, and spinach (Spinacia oleracea L., Chenopodiaceae) possesses a wide range of metabolites with such biological activity. Plant stress response could lead to the production of metabolites with high value for human health and this could be a tool to enhance the production of molecules with antioxidant activity in plants.RESULTS:
Data reported in this paper confirm the antioxidant properties of spinach plants, and show a strong antiproliferative activity of leaf extract on HT-29 human cell line. Besides, the hypoxic stress seems to affect the pool of antioxidant molecules present in spinach leaves, as verified by means of HPLC-MS/MS analysis and the aluminium chloride and ABTS assays.CONCLUSION:
Our findings represent a basis for improving the biological and pharmacological properties of spinach plants, including the use of different growth conditions to modulate the phytocomplex profile of spinach.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Oxigênio
/
Estresse Fisiológico
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Extratos Vegetais
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Spinacia oleracea
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Neoplasias
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Antineoplásicos Fitogênicos
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Antioxidantes
Limite:
Humans
Idioma:
En
Revista:
J Sci Food Agric
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Itália