Meta-analysis of the risk of cataract in type 2 diabetes.
BMC Ophthalmol
; 14: 94, 2014 Jul 24.
Article
em En
| MEDLINE
| ID: mdl-25060855
ABSTRACT
BACKGROUND:
This meta-analysis aimed to investigate the association between type 2 diabetes (T2D) and the risk of cataract.METHODS:
Databases of Pubmed, Embase, and SpringerLink were retrieved for observational studies published before November 2013. The odds ratio (OR) and 95% confidence interval (CI) were used for estimating the association. All statistical analyses were performed by Stata 10.0 software.RESULTS:
A total of 8 studies involving 20837 subjects were included in the meta-analysis. The risk of any cataract (AC) in T2D patients was higher than that in non-diabetic subjects (OR = 1.97, 95% CI 1.45-2.67, P < 0.001). The risks of cortical cataract posterior (CC) (OR = 1.68, 95% CI 1.47-1.91, P < 0.001) and posterior subcapsular (PSC) (OR = 1.55, 95% CI 1.27-1.90, P < 0.001) were significantly elevated in T2D patients, while no significant association was found in nuclear sclerosis (NS) (OR = 1.36, 95% CI 0.97-1.90, P = 0.070).CONCLUSION:
T2D patients had a higher risk of cataracts, excepting NS. Special attention should be paid on the ophthalmic extermination, especially for cataract in T2D patients.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Catarata
/
Envelhecimento
/
Medição de Risco
/
Diabetes Mellitus Tipo 2
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
BMC Ophthalmol
Assunto da revista:
OFTALMOLOGIA
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
China