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A novel FcγRIIa Q27W gene variant is associated with common variable immune deficiency through defective FcγRIIa downstream signaling.
Flinsenberg, Thijs W H; Janssen, Willemijn J; Herczenik, Eszter; Boross, Peter; Nederend, Maaike; Jongeneel, Lieneke H; Scholman, Rianne C; Boelens, Jaap-Jan; Maas, Coen; van Gijn, Marielle E; van Montfrans, Joris M; Leusen, Jeanette H; Boes, Marianne.
Afiliação
  • Flinsenberg TWH; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • Janssen WJ; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • Herczenik E; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • Boross P; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • Nederend M; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • Jongeneel LH; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • Scholman RC; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • Boelens JJ; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • Maas C; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • van Gijn ME; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • van Montfrans JM; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • Leusen JH; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
  • Boes M; Laboratory of Translational Immunology, University Medical Center Utrecht, Wilhelmina Children's Hospital, Utrecht, The Netherlands. Electronic address: mboes@umcutrecht.nl.
Clin Immunol ; 155(1): 108-117, 2014 Nov.
Article em En | MEDLINE | ID: mdl-25242138
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptores de IgG / Imunodeficiência de Variável Comum Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Humans / Male Idioma: En Revista: Clin Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptores de IgG / Imunodeficiência de Variável Comum Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Humans / Male Idioma: En Revista: Clin Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Holanda