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Discovery of 4-aminoquinazoline--urea derivatives as Aurora kinase inhibitors with antiproliferative activity.
Cai, Jin; Li, Lili; Hong, Kwon Ho; Wu, Xiaoqing; Chen, Junqing; Wang, Peng; Cao, Meng; Zong, Xi; Ji, Min.
Afiliação
  • Cai J; School of Chemistry and Chemical Engineering, Institute of Pharmaceutical Engineering, Southeast University, 87 Dingjiaqiao, Nanjing, Jiangsu 210096, PR China.
  • Li L; School of Chemistry and Chemical Engineering, Institute of Pharmaceutical Engineering, Southeast University, 87 Dingjiaqiao, Nanjing, Jiangsu 210096, PR China.
  • Hong KH; Department of Medicinal Chemistry and The Institute for Therapeutics Discovery and Development, University of Minnesota, 717 Delaware Street SE, Minneapolis, MN 55414, USA.
  • Wu X; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
  • Chen J; School of Chemistry and Chemical Engineering, Institute of Pharmaceutical Engineering, Southeast University, 87 Dingjiaqiao, Nanjing, Jiangsu 210096, PR China.
  • Wang P; School of Biological Science & Medical Engineering, Southeast University, Nanjing 210096, PR China.
  • Cao M; School of Biological Science & Medical Engineering, Southeast University, Nanjing 210096, PR China.
  • Zong X; School of Chemistry and Chemical Engineering, Institute of Pharmaceutical Engineering, Southeast University, 87 Dingjiaqiao, Nanjing, Jiangsu 210096, PR China.
  • Ji M; School of Chemistry and Chemical Engineering, Institute of Pharmaceutical Engineering, Southeast University, 87 Dingjiaqiao, Nanjing, Jiangsu 210096, PR China; School of Biological Science & Medical Engineering, Southeast University, Nanjing 210096, PR China. Electronic address: jimin@seu.edu.cn
Bioorg Med Chem ; 22(21): 5813-23, 2014 Nov 01.
Article em En | MEDLINE | ID: mdl-25270403
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinazolinas / Ureia / Inibidores de Proteínas Quinases / Aurora Quinase A / Aurora Quinase B / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinazolinas / Ureia / Inibidores de Proteínas Quinases / Aurora Quinase A / Aurora Quinase B / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article