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Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide.
Freudenthal, Bret D; Beard, William A; Perera, Lalith; Shock, David D; Kim, Taejin; Schlick, Tamar; Wilson, Samuel H.
Afiliação
  • Freudenthal BD; Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, PO Box 12233, Research Triangle Park, North Carolina 27709-2233, USA.
  • Beard WA; Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, PO Box 12233, Research Triangle Park, North Carolina 27709-2233, USA.
  • Perera L; Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, PO Box 12233, Research Triangle Park, North Carolina 27709-2233, USA.
  • Shock DD; Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, PO Box 12233, Research Triangle Park, North Carolina 27709-2233, USA.
  • Kim T; 1] Department of Chemistry, New York University, and NYU-ECNU Center for Computational Chemistry at NYU Shanghai, 10th Floor Silver Center, 100 Washington Square East, New York, New York 10003, USA [2] Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, New
  • Schlick T; 1] Department of Chemistry, New York University, and NYU-ECNU Center for Computational Chemistry at NYU Shanghai, 10th Floor Silver Center, 100 Washington Square East, New York, New York 10003, USA [2] Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, New
  • Wilson SH; Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, PO Box 12233, Research Triangle Park, North Carolina 27709-2233, USA.
Nature ; 517(7536): 635-9, 2015 Jan 29.
Article em En | MEDLINE | ID: mdl-25409153

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Mutagênese / DNA Polimerase beta / Citotoxinas / Nucleotídeos de Desoxiguanina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Mutagênese / DNA Polimerase beta / Citotoxinas / Nucleotídeos de Desoxiguanina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos