Evaluation of membrane filtration system using The "Pore Diffusion" for eliminating viruses.
J Vet Med Sci
; 77(6): 733-7, 2015 Jun.
Article
em En
| MEDLINE
| ID: mdl-25715959
Here, we report a first study of virus removal by a novel membrane filtration system, named the "Pore Diffusion". The "Pore Diffusion" manipulated the direction of circulating flow from vertical to parallel to the membrane, thereby achieved to alter the trans-membrane pressure as low as possible. We compared the viral activity between before and after filtration by both infectivity assay and real-time reverse transcription-PCR. Among 4 "Pore Diffusion" modules tested, the big module with average pore size of 80 nm showed the highest log reduction value of viral activity. Our study shows the possibility of "The Pore Diffusion" to filtrate viruses from bioproducts without increasing the trans-membrane pressure, so that the filtration process can be carried out effectively and economically.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vírus
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Produtos Biológicos
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Filtração
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Membranas Artificiais
Tipo de estudo:
Evaluation_studies
Idioma:
En
Revista:
J Vet Med Sci
Assunto da revista:
MEDICINA VETERINARIA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Japão