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High turnover of tissue factor enables efficient intracellular delivery of antibody-drug conjugates.
de Goeij, Bart E C G; Satijn, David; Freitag, Claudia M; Wubbolts, Richard; Bleeker, Wim K; Khasanov, Alisher; Zhu, Tong; Chen, Gary; Miao, David; van Berkel, Patrick H C; Parren, Paul W H I.
Afiliação
  • de Goeij BE; Genmab, Utrecht, the Netherlands. BGO@genmab.com.
  • Satijn D; Genmab, Utrecht, the Netherlands.
  • Freitag CM; Genmab, Utrecht, the Netherlands.
  • Wubbolts R; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
  • Bleeker WK; Genmab, Utrecht, the Netherlands.
  • Khasanov A; Concortis Biosystems Corp., San Diego, California.
  • Zhu T; Concortis Biosystems Corp., San Diego, California.
  • Chen G; Concortis Biosystems Corp., San Diego, California.
  • Miao D; Concortis Biosystems Corp., San Diego, California.
  • van Berkel PH; Genmab, Utrecht, the Netherlands.
  • Parren PW; Genmab, Utrecht, the Netherlands. Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark. Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
Mol Cancer Ther ; 14(5): 1130-40, 2015 May.
Article em En | MEDLINE | ID: mdl-25724665
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator VIIa / Imunotoxinas / Receptores ErbB / Neoplasias Experimentais / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator VIIa / Imunotoxinas / Receptores ErbB / Neoplasias Experimentais / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda