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Design and synthesis of novel anti-tuberculosis agents from the celecoxib pharmacophore.
Salunke, Santosh B; Azad, Abul K; Kapuriya, Naval P; Balada-Llasat, Joan-Miquel; Pancholi, Preeti; Schlesinger, Larry S; Chen, Ching-Shih.
Afiliação
  • Salunke SB; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, 500 West 12th Avenue, Columbus, OH 43210, United States.
  • Azad AK; Center for Microbial Interface Biology, The Ohio State University, 460 W 12th Avenue, Columbus, OH 43210, United States; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Wexner Medical Center, 460 W 12th Avenue, Columbus, OH 43210, United States.
  • Kapuriya NP; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, 500 West 12th Avenue, Columbus, OH 43210, United States; Division of Pharmaceutical and Organic Chemistry, M. & N. Virani Science College, Saurashtra University, Rajkot 360005, Gujarat, India.
  • Balada-Llasat JM; Department of Pathology, The Ohio State University, 410 W. 10th Avenue, Columbus, OH 43210, United States.
  • Pancholi P; Department of Pathology, The Ohio State University, 410 W. 10th Avenue, Columbus, OH 43210, United States.
  • Schlesinger LS; Center for Microbial Interface Biology, The Ohio State University, 460 W 12th Avenue, Columbus, OH 43210, United States; Department of Microbial Infection and Immunity, The Ohio State University College of Medicine, Wexner Medical Center, 460 W 12th Avenue, Columbus, OH 43210, United States. Electro
  • Chen CS; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, 500 West 12th Avenue, Columbus, OH 43210, United States; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan. Electronic address: chen.844@osu.edu.
Bioorg Med Chem ; 23(9): 1935-43, 2015 May 01.
Article em En | MEDLINE | ID: mdl-25818768

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Mycobacterium smegmatis / Farmacorresistência Bacteriana Múltipla / Celecoxib / Mycobacterium tuberculosis / Antituberculosos Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Mycobacterium smegmatis / Farmacorresistência Bacteriana Múltipla / Celecoxib / Mycobacterium tuberculosis / Antituberculosos Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos