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Targeting matrix metalloproteinases with intravenous doxycycline in severe sepsis--A randomised placebo-controlled pilot trial.
Nukarinen, Eija; Tervahartiala, Taina; Valkonen, Miia; Hynninen, Marja; Kolho, Elina; Pettilä, Ville; Sorsa, Timo; Backman, Janne; Hästbacka, Johanna.
Afiliação
  • Nukarinen E; Intensive Care Medicine, Department of Perioperative, Intensive Care and Pain Medicine University of Helsinki and Helsinki University Hospital, PB 340, 00029 HUS, Finland. Electronic address: eija.nukarinen@hus.fi.
  • Tervahartiala T; Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, PB 263, 00029 HUS, Finland.
  • Valkonen M; Intensive Care Medicine, Department of Perioperative, Intensive Care and Pain Medicine University of Helsinki and Helsinki University Hospital, PB 340, 00029 HUS, Finland.
  • Hynninen M; Intensive Care Medicine, Department of Perioperative, Intensive Care and Pain Medicine University of Helsinki and Helsinki University Hospital, PB 340, 00029 HUS, Finland.
  • Kolho E; Department of Infectious Diseases, University of Helsinki and Helsinki University Hospital, PB 340, 00029 HUS, Finland.
  • Pettilä V; Intensive Care Medicine, Department of Perioperative, Intensive Care and Pain Medicine University of Helsinki and Helsinki University Hospital, PB 340, 00029 HUS, Finland.
  • Sorsa T; Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, PB 263, 00029 HUS, Finland; Division of Periodontology, Department of Dental Medicine, Karolinska Institutet, PB 4046, 141 04 Huddinge, Sweden.
  • Backman J; Department of Clinical Pharmacology, University of Helsinki and HUSLAB, Helsinki University Hospital, PB 705, 00029 HUS, Finland.
  • Hästbacka J; Intensive Care Medicine, Department of Perioperative, Intensive Care and Pain Medicine University of Helsinki and Helsinki University Hospital, PB 340, 00029 HUS, Finland.
Pharmacol Res ; 99: 44-51, 2015 Sep.
Article em En | MEDLINE | ID: mdl-26008138
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doxiciclina / Sepse / Inibidores de Metaloproteinases de Matriz / Antibacterianos Tipo de estudo: Clinical_trials Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doxiciclina / Sepse / Inibidores de Metaloproteinases de Matriz / Antibacterianos Tipo de estudo: Clinical_trials Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2015 Tipo de documento: Article