Structural integrity of the ribonuclease H domain in HIV-1 reverse transcriptase.

Slack, Ryan L; Spiriti, Justin; Ahn, Jinwoo; Parniak, Michael A; Zuckerman, Daniel M; Ishima, Rieko

Slack, Ryan L; Spiriti, Justin; Ahn, Jinwoo; Parniak, Michael A; Zuckerman, Daniel M; Ishima, Rieko.

Afiliação

Slack RL; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, 15260.
Spiriti J; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, 15260.
Ahn J; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, 15260.
Parniak MA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, 15260.
Zuckerman DM; Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, 15260.
Ishima R; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, 15260.

Proteins ; 83(8): 1526-38, 2015 Aug.

Article em En | MEDLINE | ID: mdl-26061827

Assuntos

Transcriptase Reversa do HIV/química; Ribonuclease H/química; Simulação de Dinâmica Molecular; Mutação; Ressonância Magnética Nuclear Biomolecular; Estrutura Terciária de Proteína

Palavras-chave

HIV; NMR; enzyme; maturation; protein; proteolysis; virus

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribonuclease H / Transcriptase Reversa do HIV Tipo de estudo: Prognostic_studies Idioma: En Revista: Proteins Assunto da revista: BIOQUIMICA Ano de publicação: 2015 Tipo de documento: Article

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