Ca(2+) clearance by plasmalemmal NCLX, Li(+)-permeable Na(+)/Ca(2+) exchanger, is required for the sustained exocytosis in rat insulinoma INS-1 cells.

Han, Young-Eun; Ryu, Shin-Young; Park, Sun-Hyun; Lee, Kyu-Hee; Lee, Suk-Ho; Ho, Won-Kyung

Han, Young-Eun; Ryu, Shin-Young; Park, Sun-Hyun; Lee, Kyu-Hee; Lee, Suk-Ho; Ho, Won-Kyung.

Afiliação

Han YE; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea.
Ryu SY; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea.
Park SH; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea.
Lee KH; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea.
Lee SH; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea.
Ho WK; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea. wonkyung@snu.ac.kr.

Pflugers Arch ; 467(12): 2461-72, 2015 Dec.

Article em En | MEDLINE | ID: mdl-26100674

Assuntos

Cálcio/metabolismo; Membrana Celular/metabolismo; Exocitose; Células Secretoras de Insulina/metabolismo; Lítio/metabolismo; Trocador de Sódio e Cálcio/metabolismo; Potenciais de Ação; Animais; Linhagem Celular Tumoral; Células Cultivadas; Células Secretoras de Insulina/efeitos dos fármacos; Potencial da Membrana Mitocondrial; Camundongos; Camundongos Endogâmicos C57BL; Peptídeos/farmacologia; Ratos; Trocador de Sódio e Cálcio/genética

Palavras-chave

Ca2+ transport; Capacitance; Exocytosis; Na+/Ca2+ exchanger; Pancreatic ß-cell

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Membrana Celular / Cálcio / Trocador de Sódio e Cálcio / Células Secretoras de Insulina / Exocitose / Lítio Limite: Animals Idioma: En Revista: Pflugers Arch Ano de publicação: 2015 Tipo de documento: Article

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