[Detection of the BCR-ABL fusion: Comparative analysis of six commercially available FISH fusion probes]. / Detektion der BCR-ABL-Fusion : Vergleichende Analyse sechs kommerzieller FISH-Sondensätze.
Pathologe
; 36(4): 372-84, 2015 Jul.
Article
em De
| MEDLINE
| ID: mdl-26175197
Chronic myeloid leukemia (CML) is diagnostically defined by the reciprocal translocation t(9;22)(q34;q11). This aberration can be detected by the BCR-ABL fluorescence in situ hybridization (FISH) technique. This article presents a comparative analysis of different commercially available FISH probes and different FISH protocols in order to optimize this technique on formalin-fixed and paraffin-embedded bone marrow trephine biopsies.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Medula Óssea
/
Leucemia Mielogênica Crônica BCR-ABL Positiva
/
Proteínas de Fusão bcr-abl
/
Hibridização in Situ Fluorescente
Tipo de estudo:
Diagnostic_studies
/
Guideline
Limite:
Humans
Idioma:
De
Revista:
Pathologe
Ano de publicação:
2015
Tipo de documento:
Article