Iodine-Promoted Construction of Polysubstituted 2,3-Dihydropyrroles from Chalcones and ß-Enamine Ketones (Esters).
Org Lett
; 17(15): 3690-3, 2015 Aug 07.
Article
em En
| MEDLINE
| ID: mdl-26176324
A novel approach for the synthesis of a variety of polysubstituted trans-2,3-dihydropyrroles from a wide range of chalcones and ß-enamine ketones (esters) via iodine-promoted tandem Michael/cyclization sequence has been developed, affording the desired products in moderate to excellent yields. This methodology is a highly efficient, convenient way to access functionalized 2,3-dihydropyrroles from readily accessible substrates under mild reaction conditions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pirróis
/
Chalconas
/
Iodo
/
Cetonas
Idioma:
En
Revista:
Org Lett
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2015
Tipo de documento:
Article