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Effects of Air Pollution and the Introduction of the London Low Emission Zone on the Prevalence of Respiratory and Allergic Symptoms in Schoolchildren in East London: A Sequential Cross-Sectional Study.
Wood, Helen E; Marlin, Nadine; Mudway, Ian S; Bremner, Stephen A; Cross, Louise; Dundas, Isobel; Grieve, Andrew; Grigg, Jonathan; Jamaludin, Jeenath B; Kelly, Frank J; Lee, Tak; Sheikh, Aziz; Walton, Robert; Griffiths, Christopher J.
Afiliação
  • Wood HE; MRC-PHE Centre for Environment and Health, King's College London, London, United Kingdom.
  • Marlin N; Asthma UK Centre for Applied Asthma Research, Centre for Primary Care and Public Health, Blizard Institute, Queen Mary University of London, London, United Kingdom.
  • Mudway IS; MRC-PHE Centre for Environment and Health, King's College London, London, United Kingdom.
  • Bremner SA; Asthma UK Centre for Applied Asthma Research, Centre for Primary Care and Public Health, Blizard Institute, Queen Mary University of London, London, United Kingdom.
  • Cross L; Asthma UK Centre for Applied Asthma Research, Centre for Primary Care and Public Health, Blizard Institute, Queen Mary University of London, London, United Kingdom.
  • Dundas I; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
  • Grieve A; MRC-PHE Centre for Environment and Health, King's College London, London, United Kingdom.
  • Grigg J; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
  • Jamaludin JB; MRC-PHE Centre for Environment and Health, King's College London, London, United Kingdom; Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Kelantan, Malaysia.
  • Kelly FJ; MRC-PHE Centre for Environment and Health, King's College London, London, United Kingdom.
  • Lee T; MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom; Allergy Centre, HK Sanatorium and Hospital, Hong Kong, China.
  • Sheikh A; Allergy & Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, United Kingdom; Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, United States of America.
  • Walton R; Asthma UK Centre for Applied Asthma Research, Centre for Primary Care and Public Health, Blizard Institute, Queen Mary University of London, London, United Kingdom.
  • Griffiths CJ; Asthma UK Centre for Applied Asthma Research, Centre for Primary Care and Public Health, Blizard Institute, Queen Mary University of London, London, United Kingdom.
PLoS One ; 10(8): e0109121, 2015.
Article em En | MEDLINE | ID: mdl-26295579
The adverse effects of traffic-related air pollution on children's respiratory health have been widely reported, but few studies have evaluated the impact of traffic-control policies designed to reduce urban air pollution. We assessed associations between traffic-related air pollutants and respiratory/allergic symptoms amongst 8-9 year-old schoolchildren living within the London Low Emission Zone (LEZ). Information on respiratory/allergic symptoms was obtained using a parent-completed questionnaire and linked to modelled annual air pollutant concentrations based on the residential address of each child, using a multivariable mixed effects logistic regression analysis. Exposure to traffic-related air pollutants was associated with current rhinitis: NOx (OR 1.01, 95% CI 1.00-1.02), NO2 (1.03, 1.00-1.06), PM10 (1.16, 1.04-1.28) and PM2.5 (1.38, 1.08-1.78), all per µg/m3 of pollutant, but not with other respiratory/allergic symptoms. The LEZ did not reduce ambient air pollution levels, or affect the prevalence of respiratory/allergic symptoms over the period studied. These data confirm the previous association between traffic-related air pollutant exposures and symptoms of current rhinitis. Importantly, the London LEZ has not significantly improved air quality within the city, or the respiratory health of the resident population in its first three years of operation. This highlights the need for more robust measures to reduce traffic emissions.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hipersensibilidade Respiratória / Emissões de Veículos / Poluição do Ar / Exposição Ambiental / Rinite Alérgica Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Female / Humans / Male País/Região como assunto: Europa Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hipersensibilidade Respiratória / Emissões de Veículos / Poluição do Ar / Exposição Ambiental / Rinite Alérgica Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Female / Humans / Male País/Região como assunto: Europa Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido