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Multidisciplinary approach of lumbo-sacral chordoma: From oncological treatment to reconstructive surgery.
Garofalo, Fabio; di Summa, Pietro G; Christoforidis, Dimitrios; Pracht, Marc; Laudato, Pietro; Cherix, Stéphane; Bouchaab, Hanan; Raffoul, Wassim; Demartines, Nicolas; Matter, Maurice.
Afiliação
  • Garofalo F; Department of Visceral Surgery, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
  • di Summa PG; Department of Plastic and Reconstructive Surgery, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
  • Christoforidis D; Department of Visceral Surgery, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
  • Pracht M; Department of Surgery, Hospital Civico, Lugano, Switzerland.
  • Laudato P; Department of Oncology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
  • Cherix S; Department of Orthopedics, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
  • Bouchaab H; Department of Orthopedics, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
  • Raffoul W; Department of Radio-Oncology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
  • Demartines N; Department of Plastic and Reconstructive Surgery, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
  • Matter M; Department of Visceral Surgery, University Hospital of Lausanne (CHUV), Lausanne, Switzerland.
J Surg Oncol ; 112(5): 544-54, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26496212
ABSTRACT
Lumbo-sacral chordoma is a rare, slow-growing tumor, arising from embryonic nothocordal remnants. Wide en bloc excision with clear margins remains mandatory to achieve satisfactory recurrence rates and disease-free survival. No chemotherapy has been demonstrated to be effective and radiotherapy is only marginally effective. Tyrosine kinase receptor inhibitors have showed encouraging results in locally advanced and metastatic chordoma. Reconstructive surgery may become very complex. Multidisciplinary approach in tertiary hospitals is always necessary.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sacro / Neoplasias da Coluna Vertebral / Cordoma / Procedimentos de Cirurgia Plástica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Surg Oncol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Suíça
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sacro / Neoplasias da Coluna Vertebral / Cordoma / Procedimentos de Cirurgia Plástica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Surg Oncol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Suíça