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A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.
Dale, Trevor; Clarke, Paul A; Esdar, Christina; Waalboer, Dennis; Adeniji-Popoola, Olajumoke; Ortiz-Ruiz, Maria-Jesus; Mallinger, Aurélie; Samant, Rahul S; Czodrowski, Paul; Musil, Djordje; Schwarz, Daniel; Schneider, Klaus; Stubbs, Mark; Ewan, Ken; Fraser, Elizabeth; TePoele, Robert; Court, Will; Box, Gary; Valenti, Melanie; de Haven Brandon, Alexis; Gowan, Sharon; Rohdich, Felix; Raynaud, Florence; Schneider, Richard; Poeschke, Oliver; Blaukat, Andree; Workman, Paul; Schiemann, Kai; Eccles, Suzanne A; Wienke, Dirk; Blagg, Julian.
Afiliação
  • Dale T; School of Bioscience, Cardiff University, Cardiff, UK.
  • Clarke PA; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Esdar C; Merck KGaA, Merck Serono, Darmstadt, Germany.
  • Waalboer D; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Adeniji-Popoola O; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Ortiz-Ruiz MJ; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Mallinger A; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Samant RS; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Czodrowski P; Merck KGaA, Merck Serono, Darmstadt, Germany.
  • Musil D; Merck KGaA, Merck Serono, Darmstadt, Germany.
  • Schwarz D; Merck KGaA, Merck Serono, Darmstadt, Germany.
  • Schneider K; Merck KGaA, Merck Serono, Darmstadt, Germany.
  • Stubbs M; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Ewan K; School of Bioscience, Cardiff University, Cardiff, UK.
  • Fraser E; School of Bioscience, Cardiff University, Cardiff, UK.
  • TePoele R; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Court W; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Box G; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Valenti M; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • de Haven Brandon A; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Gowan S; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Rohdich F; Merck KGaA, Merck Serono, Darmstadt, Germany.
  • Raynaud F; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Schneider R; Merck KGaA, Merck Serono, Darmstadt, Germany.
  • Poeschke O; Merck KGaA, Merck Serono, Darmstadt, Germany.
  • Blaukat A; Merck KGaA, Merck Serono, Darmstadt, Germany.
  • Workman P; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Schiemann K; Merck KGaA, Merck Serono, Darmstadt, Germany.
  • Eccles SA; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
  • Wienke D; Merck KGaA, Merck Serono, Darmstadt, Germany.
  • Blagg J; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London, SW7 3RP.
Nat Chem Biol ; 11(12): 973-980, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26502155
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Compostos de Espiro / Sondas Moleculares / Neoplasias do Colo / Quinases Ciclina-Dependentes / Inibidores de Proteínas Quinases / Quinase 8 Dependente de Ciclina Limite: Humans Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Compostos de Espiro / Sondas Moleculares / Neoplasias do Colo / Quinases Ciclina-Dependentes / Inibidores de Proteínas Quinases / Quinase 8 Dependente de Ciclina Limite: Humans Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido