A 2-(2'-hydroxyphenyl)benzothiazole (HBT)-quinoline conjugate: a highly specific fluorescent probe for Hg(2+) based on ESIPT and its application in bioimaging.
Dalton Trans
; 44(46): 20139-46, 2015 Dec 14.
Article
em En
| MEDLINE
| ID: mdl-26531056
ABSTRACT
A benzothiazole derived chemosensor L has been designed based on the excited-state intramolecular proton transfer (ESIPT) mechanism to afford a fluorescence turn-on response specifically in the presence of Hg(2+) ions over a host of biologically relevant metal ions as well as toxic heavy metal ions. The chemosensor exhibits high sensitivity with the detection limit down to 0.11 µM. The metal binding is supported by (1)H NMR titrations, ESI-MS spectral analysis and substantiated by theoretical calculations using the density functional theory. The probe shows cell membrane permeability and efficiency for the detection of Hg(2+) in HeLa cells.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fenóis
/
Quinolinas
/
Benzotiazóis
/
Corantes Fluorescentes
/
Mercúrio
Limite:
Humans
Idioma:
En
Revista:
Dalton Trans
Assunto da revista:
QUIMICA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Índia