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Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.
Tan, Justin L; Fogley, Rachel D; Flynn, Ryan A; Ablain, Julien; Yang, Song; Saint-André, Violaine; Fan, Zi Peng; Do, Brian T; Laga, Alvaro C; Fujinaga, Koh; Santoriello, Cristina; Greer, Celeste B; Kim, Yoon Jung; Clohessy, John G; Bothmer, Anne; Pandell, Nicole; Avagyan, Serine; Brogie, John E; van Rooijen, Ellen; Hagedorn, Elliott J; Shyh-Chang, Ng; White, Richard M; Price, David H; Pandolfi, Pier Paolo; Peterlin, B Matija; Zhou, Yi; Kim, Tae Hoon; Asara, John M; Chang, Howard Y; Young, Richard A; Zon, Leonard I.
Afiliação
  • Tan JL; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 0213
  • Fogley RD; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 0213
  • Flynn RA; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Ablain J; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 0213
  • Yang S; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 0213
  • Saint-André V; Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Fan ZP; Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Do BT; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Laga AC; Department of Pathology, Brigham & Women's Hospital, Boston, MA 02215, USA.
  • Fujinaga K; Departments of Medicine, Microbiology, and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Santoriello C; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 0213
  • Greer CB; Department of Pharmacology, School of Medicine, Yale University, New Haven, CT 06520, USA.
  • Kim YJ; Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX 75080, USA.
  • Clohessy JG; Cancer Research Institute, Beth Israel Deaconess Cancer Center, and Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA; Preclinical Murine Pharmacogenetics Facility, Beth Israel Deaconess Medical Center, Harvard Medical School, B
  • Bothmer A; Cancer Research Institute, Beth Israel Deaconess Cancer Center, and Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
  • Pandell N; Preclinical Murine Pharmacogenetics Facility, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
  • Avagyan S; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 0213
  • Brogie JE; Department of Biochemistry, University of Iowa, Iowa City, IA 52242, USA.
  • van Rooijen E; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 0213
  • Hagedorn EJ; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 0213
  • Shyh-Chang N; Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore.
  • White RM; Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY 10065, USA.
  • Price DH; Department of Biochemistry, University of Iowa, Iowa City, IA 52242, USA.
  • Pandolfi PP; Cancer Research Institute, Beth Israel Deaconess Cancer Center, and Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
  • Peterlin BM; Departments of Medicine, Microbiology, and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Zhou Y; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 0213
  • Kim TH; Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX 75080, USA.
  • Asara JM; Division of Signal Transduction, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Chang HY; Center for Personal Dynamic Regulomes, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Young RA; Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Zon LI; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 0213
Mol Cell ; 62(1): 34-46, 2016 Apr 07.
Article em En | MEDLINE | ID: mdl-27058786
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Proteínas de Ligação a RNA / Fator B de Elongação Transcricional Positiva / Melanoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Proteínas de Ligação a RNA / Fator B de Elongação Transcricional Positiva / Melanoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2016 Tipo de documento: Article