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Traumatic Brain Injury Imaging in the Second Near-Infrared Window with a Molecular Fluorophore.
Zhang, Xiao-Dong; Wang, Huasen; Antaris, Alexander L; Li, Lulin; Diao, Shuo; Ma, Rui; Nguyen, Andy; Hong, Guosong; Ma, Zhuoran; Wang, Joy; Zhu, Shoujun; Castellano, Joseph M; Wyss-Coray, Tony; Liang, Yongye; Luo, Jian; Dai, Hongjie.
Afiliação
  • Zhang XD; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
  • Wang H; Department of Physics, School of Science, Tianjin University, Tianjin, 300354, P. R. China.
  • Antaris AL; Department of Materials Science and Engineering, South University of Science and Technology of China, Shenzhen, 518055, P. R. China.
  • Li L; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
  • Diao S; Palo Alto Veterans Institute for Research, VA Palo Alto Health Care System, Palo Alto, CA, 94304, USA.
  • Ma R; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
  • Nguyen A; Department of Materials Science and Engineering, South University of Science and Technology of China, Shenzhen, 518055, P. R. China.
  • Hong G; Palo Alto Veterans Institute for Research, VA Palo Alto Health Care System, Palo Alto, CA, 94304, USA.
  • Ma Z; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
  • Wang J; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
  • Zhu S; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
  • Castellano JM; Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
  • Wyss-Coray T; Department of Neurology and Neurological Sciences, School of Medicine, Stanford University, Stanford, CA, 94305, USA.
  • Liang Y; Department of Neurology and Neurological Sciences, School of Medicine, Stanford University, Stanford, CA, 94305, USA.
  • Luo J; Center for Tissue Regeneration, Repair and Restoration, VA Palo Alto Health Care System, Palo Alto, CA, 94304, USA.
  • Dai H; Department of Materials Science and Engineering, South University of Science and Technology of China, Shenzhen, 518055, P. R. China.
Adv Mater ; 28(32): 6872-9, 2016 Aug.
Article em En | MEDLINE | ID: mdl-27253071
ABSTRACT
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. A bright, renal-excreted, and biocompatible near-infrared II fluorophore for in vivo imaging of TBI is designed. A transient hypoperfusion in the injured cerebral region, followed by fluorophore leakage, is observed. NIR-II fluorophores can provide noninvasive assessment of TBI.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Corantes Fluorescentes / Lesões Encefálicas Traumáticas Limite: Animals Idioma: En Revista: Adv Mater Assunto da revista: BIOFISICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Corantes Fluorescentes / Lesões Encefálicas Traumáticas Limite: Animals Idioma: En Revista: Adv Mater Assunto da revista: BIOFISICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos