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Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase.
Palencia, Andrés; Li, Xianfeng; Bu, Wei; Choi, Wai; Ding, Charles Z; Easom, Eric E; Feng, Lisa; Hernandez, Vincent; Houston, Paul; Liu, Liang; Meewan, Maliwan; Mohan, Manisha; Rock, Fernando L; Sexton, Holly; Zhang, Suoming; Zhou, Yasheen; Wan, Baojie; Wang, Yuehong; Franzblau, Scott G; Woolhiser, Lisa; Gruppo, Veronica; Lenaerts, Anne J; O'Malley, Theresa; Parish, Tanya; Cooper, Christopher B; Waters, M Gerard; Ma, Zhenkun; Ioerger, Thomas R; Sacchettini, James C; Rullas, Joaquín; Angulo-Barturen, Iñigo; Pérez-Herrán, Esther; Mendoza, Alfonso; Barros, David; Cusack, Stephen; Plattner, Jacob J; Alley, M R K.
Afiliação
  • Palencia A; European Molecular Biology Laboratory, Grenoble, France.
  • Li X; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Bu W; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Choi W; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Ding CZ; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Easom EE; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Feng L; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Hernandez V; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Houston P; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Liu L; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Meewan M; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Mohan M; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Rock FL; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Sexton H; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Zhang S; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Zhou Y; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Wan B; Institute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Wang Y; Institute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Franzblau SG; Institute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois, USA.
  • Woolhiser L; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
  • Gruppo V; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
  • Lenaerts AJ; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
  • O'Malley T; TB Discovery Research, Infectious Disease Research Institute, Seattle, Washington, USA.
  • Parish T; TB Discovery Research, Infectious Disease Research Institute, Seattle, Washington, USA.
  • Cooper CB; Global Alliance for TB Drug Development, New York, New York, USA.
  • Waters MG; Global Alliance for TB Drug Development, New York, New York, USA.
  • Ma Z; Global Alliance for TB Drug Development, New York, New York, USA.
  • Ioerger TR; Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
  • Sacchettini JC; Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
  • Rullas J; Tres Cantos Medicines Development Campus, GlaxoSmithKline, Tres Cantos, Spain.
  • Angulo-Barturen I; Tres Cantos Medicines Development Campus, GlaxoSmithKline, Tres Cantos, Spain.
  • Pérez-Herrán E; Tres Cantos Medicines Development Campus, GlaxoSmithKline, Tres Cantos, Spain.
  • Mendoza A; Tres Cantos Medicines Development Campus, GlaxoSmithKline, Tres Cantos, Spain.
  • Barros D; Tres Cantos Medicines Development Campus, GlaxoSmithKline, Tres Cantos, Spain.
  • Cusack S; European Molecular Biology Laboratory, Grenoble, France.
  • Plattner JJ; Anacor Pharmaceuticals, Palo Alto, California, USA.
  • Alley MR; Anacor Pharmaceuticals, Palo Alto, California, USA dickon_alley@mac.com.
Antimicrob Agents Chemother ; 60(10): 6271-80, 2016 10.
Article em En | MEDLINE | ID: mdl-27503647
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Síntese de Proteínas / Leucina-tRNA Ligase / Mycobacterium tuberculosis / Antituberculosos Limite: Animals / Female / Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2016 Tipo de documento: Article País de afiliação: França
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores da Síntese de Proteínas / Leucina-tRNA Ligase / Mycobacterium tuberculosis / Antituberculosos Limite: Animals / Female / Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2016 Tipo de documento: Article País de afiliação: França