Proteinuria causes dysfunctional autophagy in the proximal tubule.

Nolin, Angela C; Mulhern, Ryan M; Panchenko, Maria V; Pisarek-Horowitz, Anna; Wang, Zhiyong; Shirihai, Orian; Borkan, Steven C; Havasi, Andrea

Nolin, Angela C; Mulhern, Ryan M; Panchenko, Maria V; Pisarek-Horowitz, Anna; Wang, Zhiyong; Shirihai, Orian; Borkan, Steven C; Havasi, Andrea.

Afiliação

Nolin AC; Renal Section, Department of Medicine, Boston University, Boston, Massachusetts.
Mulhern RM; Renal Section, Department of Medicine, Boston University, Boston, Massachusetts.
Panchenko MV; Department of Pathology, Boston University, Boston, Massachusetts; and.
Pisarek-Horowitz A; Renal Section, Department of Medicine, Boston University, Boston, Massachusetts.
Wang Z; Renal Section, Department of Medicine, Boston University, Boston, Massachusetts.
Shirihai O; Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.
Borkan SC; Renal Section, Department of Medicine, Boston University, Boston, Massachusetts.
Havasi A; Renal Section, Department of Medicine, Boston University, Boston, Massachusetts; ahavasi@bu.edu.

Am J Physiol Renal Physiol ; 311(6): F1271-F1279, 2016 12 01.

Article em En | MEDLINE | ID: mdl-27582098

Assuntos

Autofagossomos/metabolismo; Autofagia/fisiologia; Túbulos Renais Proximais/metabolismo; Proteinúria/metabolismo; Animais; Linhagem Celular; Humanos; Camundongos; Fosforilação; Serina-Treonina Quinases TOR/metabolismo

Palavras-chave

albumin; autophagy; mTOR; proteinuria; reabsorption

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteinúria / Autofagia / Autofagossomos / Túbulos Renais Proximais Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Am J Physiol Renal Physiol Assunto da revista: FISIOLOGIA / NEFROLOGIA Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google