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Tetrahydroindazole derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists.
Matthews, Jay M; McNally, James J; Connolly, Peter J; Xia, Mingde; Zhu, Bin; Black, Shawn; Chen, Cailin; Hou, Cuifen; Liang, Yin; Tang, Yuting; Macielag, Mark J.
Afiliação
  • Matthews JM; Janssen Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA 19477, USA(†).
  • McNally JJ; Janssen Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA 19477, USA(†).
  • Connolly PJ; Janssen Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA 19477, USA(†).
  • Xia M; Janssen Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA 19477, USA(†).
  • Zhu B; Janssen Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA 19477, USA(†).
  • Black S; Janssen Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA 19477, USA(†).
  • Chen C; Janssen Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA 19477, USA(†).
  • Hou C; Janssen Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA 19477, USA(†).
  • Liang Y; Janssen Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA 19477, USA(†).
  • Tang Y; Janssen Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA 19477, USA(†).
  • Macielag MJ; Janssen Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA 19477, USA(†).
Bioorg Med Chem Lett ; 26(21): 5346-5349, 2016 11 01.
Article em En | MEDLINE | ID: mdl-27671496
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor CB1 de Canabinoide / Agonismo Inverso de Drogas / Indazóis Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor CB1 de Canabinoide / Agonismo Inverso de Drogas / Indazóis Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article