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Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.
Fei, Dennis Liang; Motowski, Hayley; Chatrikhi, Rakesh; Prasad, Sameer; Yu, Jovian; Gao, Shaojian; Kielkopf, Clara L; Bradley, Robert K; Varmus, Harold.
Afiliação
  • Fei DL; Cancer Biology Section, Cancer Genetics Branch, National Human Genome Research Institute, Bethesda, United States Of America.
  • Motowski H; Department of Medicine, Meyer Cancer Center, Weill Cornell Medicine, New York, United States Of America.
  • Chatrikhi R; Cancer Biology Section, Cancer Genetics Branch, National Human Genome Research Institute, Bethesda, United States Of America.
  • Prasad S; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, Rochester, United States Of America.
  • Yu J; Cancer Biology Section, Cancer Genetics Branch, National Human Genome Research Institute, Bethesda, United States Of America.
  • Gao S; Cancer Biology Section, Cancer Genetics Branch, National Human Genome Research Institute, Bethesda, United States Of America.
  • Kielkopf CL; Genetics Branch, National Cancer Institute, Bethesda, United States Of America.
  • Bradley RK; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, Rochester, United States Of America.
  • Varmus H; Computational Biology Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, United States Of America.
PLoS Genet ; 12(10): e1006384, 2016 Oct.
Article em En | MEDLINE | ID: mdl-27776121
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenocarcinoma / Processamento Alternativo / Proliferação de Células / Fator de Processamento U2AF / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenocarcinoma / Processamento Alternativo / Proliferação de Células / Fator de Processamento U2AF / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos