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A positive feedback loop involving the Wnt/ß-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma.
Wu, Chengsheng; Zhang, Hai-Feng; Gupta, Nidhi; Alshareef, Abdulraheem; Wang, Qian; Huang, Yung-Hsing; Lewis, Jamie T; Douglas, Donna N; Kneteman, Norman M; Lai, Raymond.
Afiliação
  • Wu C; Department of Laboratory Medicine and Pathology, 5142J Katz Group Centre for Pharmacy and Health Research, University of Alberta, Edmonton, Alberta, T6G 1Z2, Canada.
  • Zhang HF; Department of Laboratory Medicine and Pathology, 5142J Katz Group Centre for Pharmacy and Health Research, University of Alberta, Edmonton, Alberta, T6G 1Z2, Canada.
  • Gupta N; Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou, China.
  • Alshareef A; Department of Laboratory Medicine and Pathology, 5142J Katz Group Centre for Pharmacy and Health Research, University of Alberta, Edmonton, Alberta, T6G 1Z2, Canada.
  • Wang Q; Department of Laboratory Medicine and Pathology, 5142J Katz Group Centre for Pharmacy and Health Research, University of Alberta, Edmonton, Alberta, T6G 1Z2, Canada.
  • Huang YH; Department of Laboratory Medicine and Pathology, 5142J Katz Group Centre for Pharmacy and Health Research, University of Alberta, Edmonton, Alberta, T6G 1Z2, Canada.
  • Lewis JT; Department of Laboratory Medicine and Pathology, 5142J Katz Group Centre for Pharmacy and Health Research, University of Alberta, Edmonton, Alberta, T6G 1Z2, Canada.
  • Douglas DN; Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
  • Kneteman NM; Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
  • Lai R; Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
J Hematol Oncol ; 9(1): 120, 2016 11 08.
Article em En | MEDLINE | ID: mdl-27821172

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Linfoma Anaplásico de Células Grandes / Retroalimentação Fisiológica / Via de Sinalização Wnt Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Hematol Oncol Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Canadá

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Linfoma Anaplásico de Células Grandes / Retroalimentação Fisiológica / Via de Sinalização Wnt Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Hematol Oncol Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Canadá