Vancomycin-induced thrombocytopenia in a newborn.
Drug Metab Pers Ther
; 31(4): 235-237, 2016 12 01.
Article
em En
| MEDLINE
| ID: mdl-27849621
Neonatal thrombocytopenia is common and is frequently seen in neonatal sepsis. Drug-induced thrombocytopenia is likely to be missed unless a high index of suspicion is present. Changing of antibiotics for assumed nonresolution of sepsis may lead to persistent thrombocytopenia in a neonate if drug-induced thrombocytopenia is missed. Vancomycin-induced neonatal thrombocytopenia is rarely described in scientific literature. We describe a newborn who was diagnosed with early onset sepsis and vancomycin-induced thrombocytopenia. Other causes of thrombocytopenia such as sepsis, alloimmune thrombocytopenia, thrombosis etc. were excluded. The platelet counts normalized within 72 h of stopping vancomycin. Vancomycin-induced IgM platelet antibodies could not be done in our case (due to financial constraints), but their absence does not exclude the diagnosis of vancomycin-induced thrombocytopenia.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Trombocitopenia
/
Vancomicina
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
/
Newborn
Idioma:
En
Revista:
Drug Metab Pers Ther
Ano de publicação:
2016
Tipo de documento:
Article