Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A.

Velázquez-Moctezuma, Rodrigo; Law, Mansun; Bukh, Jens; Prentoe, Jannick

Velázquez-Moctezuma, Rodrigo; Law, Mansun; Bukh, Jens; Prentoe, Jannick.

Afiliação

Velázquez-Moctezuma R; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Hvidovre Hospital and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Law M; Department of Immunology, The Scripps Research Institute, La Jolla, California, United States of America.
Bukh J; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Hvidovre Hospital and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Prentoe J; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases and Clinical Research Centre, Hvidovre Hospital and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

PLoS Pathog ; 13(2): e1006214, 2017 02.

Article em En | MEDLINE | ID: mdl-28231271

Assuntos

Anticorpos Neutralizantes/imunologia; Hepacivirus/imunologia; Evasão da Resposta Imune/imunologia; Proteínas do Envelope Viral/imunologia; Proteínas Virais/imunologia; Anticorpos Monoclonais/imunologia; Anticorpos Antivirais/imunologia; Linhagem Celular; Epitopos de Linfócito B/imunologia; Hepatite C/imunologia; Humanos; Imunoprecipitação; Mutação; Proteínas do Envelope Viral/genética; Proteínas Virais/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Virais / Proteínas do Envelope Viral / Hepacivirus / Anticorpos Neutralizantes / Evasão da Resposta Imune Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Dinamarca

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