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Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells.
Tüysüz, Nesrin; van Bloois, Louis; van den Brink, Stieneke; Begthel, Harry; Verstegen, Monique M A; Cruz, Luis J; Hui, Lijian; van der Laan, Luc J W; de Jonge, Jeroen; Vries, Robert; Braakman, Eric; Mastrobattista, Enrico; Cornelissen, Jan J; Clevers, Hans; Ten Berge, Derk.
Afiliação
  • Tüysüz N; Department of Cell Biology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.
  • van Bloois L; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, Utrecht 3584 CG, The Netherlands.
  • van den Brink S; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Cancer Genomics.nl and University Medical Center Utrecht, Uppsalalaan 8, Utrecht 3584 CT, The Netherlands.
  • Begthel H; Foundation Hubrecht Organoid Technology (HUB), Utrecht 3584 CT, The Netherlands.
  • Verstegen MM; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Cancer Genomics.nl and University Medical Center Utrecht, Uppsalalaan 8, Utrecht 3584 CT, The Netherlands.
  • Cruz LJ; Foundation Hubrecht Organoid Technology (HUB), Utrecht 3584 CT, The Netherlands.
  • Hui L; Department of Surgery, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.
  • van der Laan LJ; Experimental Molecular Imaging, Department of Radiology, Leiden University Medical Center, Albinusdreef 2, Leiden 2333 ZA, The Netherlands.
  • de Jonge J; Shanghai Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Vries R; Department of Surgery, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.
  • Braakman E; Department of Surgery, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.
  • Mastrobattista E; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Cancer Genomics.nl and University Medical Center Utrecht, Uppsalalaan 8, Utrecht 3584 CT, The Netherlands.
  • Cornelissen JJ; Foundation Hubrecht Organoid Technology (HUB), Utrecht 3584 CT, The Netherlands.
  • Clevers H; Department of Hematology, Erasmus University Medical Center, PO Box 2040, Rotterdam 3000 CA, The Netherlands.
  • Ten Berge D; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, Utrecht 3584 CG, The Netherlands.
Nat Commun ; 8: 14578, 2017 03 06.
Article em En | MEDLINE | ID: mdl-28262686
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfolipídeos / Organoides / Colesterol / Meios de Cultivo Condicionados / Técnicas de Cultura de Tecidos / Células-Tronco Adultas / Proteína Wnt3A Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfolipídeos / Organoides / Colesterol / Meios de Cultivo Condicionados / Técnicas de Cultura de Tecidos / Células-Tronco Adultas / Proteína Wnt3A Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda