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Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.
Rubaiy, Hussein N; Ludlow, Melanie J; Henrot, Matthias; Gaunt, Hannah J; Miteva, Katarina; Cheung, Sin Ying; Tanahashi, Yasuyuki; Hamzah, Nurasyikin; Musialowski, Katie E; Blythe, Nicola M; Appleby, Hollie L; Bailey, Marc A; McKeown, Lynn; Taylor, Roger; Foster, Richard; Waldmann, Herbert; Nussbaumer, Peter; Christmann, Mathias; Bon, Robin S; Muraki, Katsuhiko; Beech, David J.
Afiliação
  • Rubaiy HN; Schools of Medicine.
  • Ludlow MJ; Schools of Medicine.
  • Henrot M; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany.
  • Gaunt HJ; Schools of Medicine.
  • Miteva K; Schools of Medicine.
  • Cheung SY; Schools of Medicine.
  • Tanahashi Y; Schools of Medicine; Faculty of Life Sciences, Kyoto Sangyo University, Kyoto 603-8555, Japan.
  • Hamzah N; Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom.
  • Musialowski KE; Schools of Medicine.
  • Blythe NM; Schools of Medicine.
  • Appleby HL; Schools of Medicine.
  • Bailey MA; Schools of Medicine.
  • McKeown L; Schools of Medicine.
  • Taylor R; Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom.
  • Foster R; Chemistry, University of Leeds, Leeds LS2 9JT, United Kingdom.
  • Waldmann H; Max-Planck-Institut für Molekulare Physiologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.
  • Nussbaumer P; Lead Discovery Center GmbH, Otto-Hahn-Strasse 15, D-44227 Dortmund, Germany.
  • Christmann M; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany.
  • Bon RS; Schools of Medicine.
  • Muraki K; School of Pharmacy, Aichi-Gakuin University, 1-100 Kusumoto, Chikusa, Nagoya 464-8650, Japan. Electronic address: kmuraki@dpc.aichi-gakuin.ac.jp.
  • Beech DJ; Schools of Medicine. Electronic address: d.j.beech@leeds.ac.uk.
J Biol Chem ; 292(20): 8158-8173, 2017 05 19.
Article em En | MEDLINE | ID: mdl-28325835

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bloqueadores dos Canais de Cálcio / Canais de Cátion TRPC Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bloqueadores dos Canais de Cálcio / Canais de Cátion TRPC Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2017 Tipo de documento: Article