Efflux Attenuates the Antibacterial Activity of Q203 in Mycobacterium tuberculosis.

Jang, Jichan; Kim, Ryangyeo; Woo, Minjeong; Jeong, Jinsun; Park, Da Eun; Kim, Guehye; Delorme, Vincent

Jang, Jichan; Kim, Ryangyeo; Woo, Minjeong; Jeong, Jinsun; Park, Da Eun; Kim, Guehye; Delorme, Vincent.

Afiliação

Jang J; Tuberculosis Research Laboratory, Institut Pasteur Korea, Seongnam, Gyeonggi, South Korea jichanjang@gnu.ac.kr vincent.delorme@ip-korea.org.
Kim R; Division of Life Science, Gyeongsang National University, Jinju, South Korea.
Woo M; Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.
Jeong J; Division of Applied Life Science (BK21plus Program), Gyeongsang National University, Jinju, South Korea.
Park DE; Tuberculosis Research Laboratory, Institut Pasteur Korea, Seongnam, Gyeonggi, South Korea.
Kim G; Tuberculosis Research Laboratory, Institut Pasteur Korea, Seongnam, Gyeonggi, South Korea.
Delorme V; Division of Applied Life Science (BK21plus Program), Gyeongsang National University, Jinju, South Korea.

Antimicrob Agents Chemother ; 61(7)2017 07.

Article em En | MEDLINE | ID: mdl-28416541

Assuntos

Mycobacterium tuberculosis/patogenicidade; Tuberculose/metabolismo; Antituberculosos/farmacologia; Proteínas de Bactérias/metabolismo; Farmacorresistência Bacteriana Múltipla/genética; Imidazóis/farmacologia; Testes de Sensibilidade Microbiana; Mycobacterium tuberculosis/efeitos dos fármacos; Oxazinas/farmacologia; Piperidinas/farmacologia; Piridinas/farmacologia; Verapamil/farmacologia; Xantenos/farmacologia

Palavras-chave

Mycobacterium tuberculosis; Q203; drug efflux; drug resistance; efflux pump inhibitors; verapamil

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose / Mycobacterium tuberculosis Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2017 Tipo de documento: Article

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