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Inhibition of HER3 activation and tumor growth with a human antibody binding to a conserved epitope formed by domain III and IV.
Schmitt, Lisa C; Rau, Alexander; Seifert, Oliver; Honer, Jonas; Hutt, Meike; Schmid, Simone; Zantow, Jonas; Hust, Michael; Dübel, Stefan; Olayioye, Monilola A; Kontermann, Roland E.
Afiliação
  • Schmitt LC; a Institute of Cell Biology and Immunology, University of Stuttgart , Stuttgart , Germany.
  • Rau A; a Institute of Cell Biology and Immunology, University of Stuttgart , Stuttgart , Germany.
  • Seifert O; a Institute of Cell Biology and Immunology, University of Stuttgart , Stuttgart , Germany.
  • Honer J; a Institute of Cell Biology and Immunology, University of Stuttgart , Stuttgart , Germany.
  • Hutt M; a Institute of Cell Biology and Immunology, University of Stuttgart , Stuttgart , Germany.
  • Schmid S; a Institute of Cell Biology and Immunology, University of Stuttgart , Stuttgart , Germany.
  • Zantow J; b Institute of Biochemistry, Biotechnology and Bioinformatics, Technische Universität Braunschweig , Braunschweig , Germany.
  • Hust M; b Institute of Biochemistry, Biotechnology and Bioinformatics, Technische Universität Braunschweig , Braunschweig , Germany.
  • Dübel S; b Institute of Biochemistry, Biotechnology and Bioinformatics, Technische Universität Braunschweig , Braunschweig , Germany.
  • Olayioye MA; a Institute of Cell Biology and Immunology, University of Stuttgart , Stuttgart , Germany.
  • Kontermann RE; c Stuttgart Research Center Systems Biology, University of Stuttgart , Stuttgart , Germany.
MAbs ; 9(5): 831-843, 2017 07.
Article em En | MEDLINE | ID: mdl-28421882
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Transdução de Sinais / Receptor ErbB-3 / Anticorpos Antineoplásicos / Epitopos / Neoplasias Experimentais Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Transdução de Sinais / Receptor ErbB-3 / Anticorpos Antineoplásicos / Epitopos / Neoplasias Experimentais Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha