Diagnostics for neonatal sepsis: current approaches and future directions.
Pediatr Res
; 82(4): 574-583, 2017 Oct.
Article
em En
| MEDLINE
| ID: mdl-28574980
ABSTRACT
Progress has been made in the reduction of morbidity and mortality from neonatal sepsis. However, diagnosis continues to rely primarily on conventional microbiologic techniques, which can be inaccurate. The objective of this review is to provide the clinician with an overview of the current information available on diagnosing this condition. We review currently available diagnostic approaches for documenting neonatal sepsis and also describe novel approaches for diagnosing infection in neonates who are under development and investigation. Substantial progress has been made with molecular approaches and further development of non-culture-based methods offer promise. The potential ability to incorporate antimicrobial resistance gene testing in addition to pathogen identification may provide a venue to incorporate a predominantly molecular platform into a larger program of neonatal care.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
DNA Bacteriano
/
Biomarcadores
/
Técnicas Bacteriológicas
/
Perfilação da Expressão Gênica
/
Técnicas de Diagnóstico Molecular
/
Sepse Neonatal
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Humans
/
Newborn
Idioma:
En
Revista:
Pediatr Res
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Mongólia