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Ndfip1 restricts mTORC1 signalling and glycolysis in regulatory T cells to prevent autoinflammatory disease.
Layman, Awo Akosua Kesewa; Deng, Guoping; O'Leary, Claire E; Tadros, Samuel; Thomas, Rajan M; Dybas, Joseph M; Moser, Emily K; Wells, Andrew D; Doliba, Nicolai M; Oliver, Paula M.
Afiliação
  • Layman AAK; Medical Scientist Training Program, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • Deng G; Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
  • O'Leary CE; Cell Pathology Division, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.
  • Tadros S; Cell Pathology Division, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.
  • Thomas RM; Cell Pathology Division, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.
  • Dybas JM; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.
  • Moser EK; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.
  • Wells AD; Cell Pathology Division, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.
  • Doliba NM; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.
  • Oliver PM; Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.
Nat Commun ; 8: 15677, 2017 06 05.
Article em En | MEDLINE | ID: mdl-28580955
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteínas de Transporte / Linfócitos T Reguladores / Alvo Mecanístico do Complexo 1 de Rapamicina / Inflamação / Proteínas de Membrana Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteínas de Transporte / Linfócitos T Reguladores / Alvo Mecanístico do Complexo 1 de Rapamicina / Inflamação / Proteínas de Membrana Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos