Spheroid growth in ovarian cancer alters transcriptome responses for stress pathways and epigenetic responses.

Paullin, Trillitye; Powell, Chase; Menzie, Christopher; Hill, Robert; Cheng, Feng; Martyniuk, Christopher J; Westerheide, Sandy D

Paullin, Trillitye; Powell, Chase; Menzie, Christopher; Hill, Robert; Cheng, Feng; Martyniuk, Christopher J; Westerheide, Sandy D.

Afiliação

Paullin T; Department of Cell Biology, Microbiology, and Molecular Biology, College of Arts and Sciences, University of South Florida, Tampa, Florida, United States of America.
Powell C; Department of Cell Biology, Microbiology, and Molecular Biology, College of Arts and Sciences, University of South Florida, Tampa, Florida, United States of America.
Menzie C; Department of Cell Biology, Microbiology, and Molecular Biology, College of Arts and Sciences, University of South Florida, Tampa, Florida, United States of America.
Hill R; Department of Cell Biology, Microbiology, and Molecular Biology, College of Arts and Sciences, University of South Florida, Tampa, Florida, United States of America.
Cheng F; Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, Florida, United States of America.
Martyniuk CJ; Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, Florida, United States of America.
Westerheide SD; Center for Environmental and Human Toxicology & Department of Physiological Sciences, UF Genetics Institute, University of Florida, Gainesville, Florida, United States of America.

PLoS One ; 12(8): e0182930, 2017.

Article em En | MEDLINE | ID: mdl-28793334

Assuntos

Metilação de DNA; Regulação Neoplásica da Expressão Gênica; Neoplasias Ovarianas/patologia; Esferoides Celulares/patologia; Transcriptoma; Linhagem Celular Tumoral; Transição Epitelial-Mesenquimal/efeitos dos fármacos; Feminino; Humanos; Neoplasias Ovarianas/genética; Esferoides Celulares/efeitos dos fármacos; Fator de Crescimento Transformador beta/farmacologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Regulação Neoplásica da Expressão Gênica / Esferoides Celulares / Metilação de DNA / Transcriptoma Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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