From pathogenesis to novel therapies in the treatment of primary biliary cholangitis.

Ronca, Vincenzo; Carbone, Marco; Bernuzzi, Francesca; Malinverno, Federica; Mousa, Hani S; Gershwin, M Eric; Invernizzi, Pietro

Ronca, Vincenzo; Carbone, Marco; Bernuzzi, Francesca; Malinverno, Federica; Mousa, Hani S; Gershwin, M Eric; Invernizzi, Pietro.

Afiliação

Ronca V; a Department of Medicine , S. Paolo Hospital, University of Milan , Milan , Italy.
Carbone M; b Program for Autoimmune Liver Diseases, International Center for Digestive Health, Department of Medicine and Surgery , University of Milano-Bicocca , Milan , Italy.
Bernuzzi F; b Program for Autoimmune Liver Diseases, International Center for Digestive Health, Department of Medicine and Surgery , University of Milano-Bicocca , Milan , Italy.
Malinverno F; b Program for Autoimmune Liver Diseases, International Center for Digestive Health, Department of Medicine and Surgery , University of Milano-Bicocca , Milan , Italy.
Mousa HS; b Program for Autoimmune Liver Diseases, International Center for Digestive Health, Department of Medicine and Surgery , University of Milano-Bicocca , Milan , Italy.
Gershwin ME; c School of Clinical Medicine , University of Cambridge , Cambridge Biomedical Campus, CB2 0AH , United Kingdom.
Invernizzi P; d Division of Rheumatology, Allergy, and Clinical Immunology , University of California at Davis , Davis , CA , USA.

Expert Rev Clin Immunol ; 13(12): 1121-1131, 2017 12.

Article em En | MEDLINE | ID: mdl-28994348

Assuntos

Ductos Biliares Intra-Hepáticos/imunologia; Ácido Quenodesoxicólico/análogos & derivados; Colangite/tratamento farmacológico; Imunoterapia/métodos; Cirrose Hepática Biliar/tratamento farmacológico; Fígado/patologia; Ácido Ursodesoxicólico/uso terapêutico; Ustekinumab/uso terapêutico; Autoimunidade; Ácido Quenodesoxicólico/uso terapêutico; Colangite/imunologia; Fibrose; Humanos; Terapia de Alvo Molecular

Palavras-chave

ASBT antagonists; FGF-19; OCA; Primary biliary cholangitis; TGR-5 agonist; Ustekinumab; autoimmune liver disease; fibrates; novel therapies; ursodeoxycholic acid

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Ursodesoxicólico / Ductos Biliares Intra-Hepáticos / Ácido Quenodesoxicólico / Colangite / Ustekinumab / Imunoterapia / Fígado / Cirrose Hepática Biliar Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Expert Rev Clin Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Itália

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