New crystal forms of the integral membrane Escherichia coli quinol:fumarate reductase suggest that ligands control domain movement.

Starbird, C A; Tomasiak, Thomas M; Singh, Prashant K; Yankovskaya, Victoria; Maklashina, Elena; Eisenbach, Michael; Cecchini, Gary; Iverson, T M

Starbird, C A; Tomasiak, Thomas M; Singh, Prashant K; Yankovskaya, Victoria; Maklashina, Elena; Eisenbach, Michael; Cecchini, Gary; Iverson, T M.

Afiliação

Starbird CA; Graduate Program in Chemical and Physical Biology, Vanderbilt University, Nashville, TN 37232, United States.
Tomasiak TM; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, United States.
Singh PK; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, United States.
Yankovskaya V; Molecular Biology Division, San Francisco VA Health Care System, San Francisco, CA 94158, United States.
Maklashina E; Molecular Biology Division, San Francisco VA Health Care System, San Francisco, CA 94158, United States; Department of Biochemistry & Biophysics, University of California, San Francisco, CA 94158, United States.
Eisenbach M; Department of Biomolecular Sciences, Weizmann Institute of Science, Israel.
Cecchini G; Molecular Biology Division, San Francisco VA Health Care System, San Francisco, CA 94158, United States.
Iverson TM; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, United States; Department of Biochemistry, Vanderbilt University, Nashville, TN 37232, United States. Electronic address: tina.iverson@vanderbilt.edu.

J Struct Biol ; 202(1): 100-104, 2018 04.

Article em En | MEDLINE | ID: mdl-29158068

Assuntos

Proteínas de Escherichia coli/química; Proteínas de Membrana/química; Oxirredutases/química; Domínios Proteicos; Sítios de Ligação; Domínio Catalítico; Cristalografia; Cristalografia por Raios X; Proteínas de Escherichia coli/metabolismo; Ligantes; Proteínas de Membrana/metabolismo; Modelos Moleculares; Oxirredutases/metabolismo; Rotação

Palavras-chave

Catalysis; Complex II; Conformational Change; Crystallography; Fumarate reductase; Lipid cubic phase; Membrane protein; Protein-protein interaction; Respiratory chain

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxirredutases / Proteínas de Escherichia coli / Domínios Proteicos / Proteínas de Membrana Idioma: En Revista: J Struct Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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